South Asian couple at a small London cafe by a window.

How much does naltrexone cost in the UK?

What you actually pay for naltrexone privately in the UK, the medicine and the clinical service, with no four-tier maze.

SR
Dr Seth Rankin
19 April 2026 5 min read

Naltrexone is the prescription medicine used in the Sinclair Method to drink less. The NHS rarely prescribes it for this, so almost everyone pays privately. There are two costs to think about: the medicine itself, and the clinical service that gets you the prescription. Here is what each runs to.

The medicine

A pack of 28 naltrexone 50mg tablets retails between about £85 and £100 from UK private pharmacies. At LoveMyLife it is £89 a pack, dispensed and delivered to your door.

How long a pack lasts comes down to how often you drink, since you take one tablet an hour before each drink and nothing on dry days. Drink most days and a pack lasts about a month; drink two or three days a week and it stretches to six or eight weeks.

Nalmefene, the alternative for anyone keen to avoid liver blood tests, is £105 a pack and taken the same way.

The clinical service

You pick how much doctor contact you want, and the medicine is always billed separately at the same price whichever route you choose.

  • Online, no appointment: £95 for your first doctor-reviewed prescription, then £49 a repeat.

  • See a doctor: £120 for a consultation by phone, video or in person. Repeats are £49 online, or £120 to see a doctor again.

  • The full programme: £499 for a doctor consultation, six months of coaching, and twelve months of repeats.

No subscription, no lock-in. The full detail is on the Sinclair Method page.

What a course actually costs

A rough guide, medicine included:

  • The lightest start: £95 online plus one £89 pack, around £184 for your first month.

  • The full programme: £499 plus the medicine you use across the year. Most people need a few packs while they find their level, then fewer as the pull fades.

Costs taper as you go, because the whole point is to want, and so buy, less over time.

Blood tests

Naltrexone comes with a liver check. Use a recent result from any provider, ask your GP for a free NHS test, or we arrange one from £49. Nalmefene needs no routine liver checks, so it carries no test cost at all.

SR
Clinically reviewed
Dr Seth Rankin
MBChB MRCGP, Founder, LoveMyLife
Reviewed by the LoveMyLife clinical team

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