Drink less, on your own terms.
The Sinclair Method uses naltrexone, taken before drinking, to gradually reduce the pull of alcohol. Doctor-led, evidence-based, no abstinence required to start. From [£TBC] a month. Pause or cancel any time.
Subscription | Doctor-led | No judgement
- GMC GP Register
- CQC-regulated clinic
- GPhC-registered pharmacy
- Today, every day.
How the Sinclair Method works
A simple, evidence-based protocol.
Complete your assessment
A 10-minute online consultation form covers your drinking history (using the AUDIT questionnaire), medical history, and the contraindications we need to screen for. No judgement, no assumptions.
Doctor review and prescribe
A doctor on the GMC GP Register reviews your assessment within one working day and discusses naltrexone with you on a video or phone consultation. If treatment is right, we prescribe and dispense.
Take naltrexone before drinking
An hour before any drinking, every time. Skip it on alcohol-free days. Most people find their consumption falls within 4 to 12 weeks; the original Finnish trials showed 78% reaching safe-drinking levels over 6 to 12 months.
What's included
Your monthly subscription bundles the medication and the clinical service.
Naltrexone
Your prescribed naltrexone, dispensed by our pharmacy and delivered in plain packaging.
Doctor reviews
An initial assessment, then a clinical review every month.
Dose adjustments
Tuning as you respond. Most people stay on a standard dose; some need adjustment.
Direct messaging
Message the clinical team between reviews. Most messages answered within one working day.
Free delivery
Plain-packaged, free delivery anywhere in the UK. No name on the box.
Pause or cancel any time
No exit fee. Take a break and come back, or stop entirely.
Is this right for you?
The Sinclair Method works best for people who want to drink less but don't necessarily want to abstain entirely. The original Finnish trials reported 78% of participants reaching safe-drinking levels over 6 to 12 months.
If you're using opioid pain medication, have severe liver disease, are pregnant, or have certain other contraindications, naltrexone isn't appropriate. The assessment will identify these. We won't prescribe and we'll talk you through alternatives.
The protocol
Naltrexone blocks the brain's opioid receptors, which is the pathway alcohol uses to reinforce itself. Taken about an hour before drinking, naltrexone gradually reduces the reward loop: drinking still happens, but the pull to drink the next one weakens over weeks and months.
The protocol is simple: take naltrexone before any drinking, every time. Skip it on alcohol-free days. The treatment runs for as long as it's working, with monthly reviews so the doctor can fine-tune the dose and check on side effects.
The Sinclair Method does not require abstinence to begin. You don't have to commit to stopping; you commit to a method that, over time, makes drinking less feel natural rather than effortful.
Pricing
Your [£TBC] monthly subscription covers the clinical service: assessment, monthly doctor reviews, dose changes, messaging, and delivery. Naltrexone is included in the subscription price.
Sinclair Method subscription (clinical service + naltrexone): [£TBC] / month
Bloods (where clinically needed): [£49] or included in your nearest blood test package
Pause or cancel any time. No exit charge.
Or come into the clinic.
Subscription clients can step into our Westfield London clinic any time, included in the monthly fee. Many people prefer to do their first consultation in person; others stay online once treatment is settled.
Westfield clinic opens early July 2026. For now, your monthly reviews run by secure video or phone.
Led by your doctors.
Dr Seth Rankin. Founder, GMC 4467397. GP for over 20 years. Founded London Doctors Clinic before LoveMyLife.
Our wider clinical team are doctors on the GMC GP Register, working with our GPhC-registered pharmacy and CQC-regulated Westfield clinic.
