Elleste Duet

Relief of menopausal symptoms including hot flushes, night sweats, mood changes, difficulty sleeping, and joint aches. Also helps protect against osteoporosis. Elleste Duet is a sequential preparation - it produces a regular monthly withdrawal bleed, making it suitable for women in perimenopause.

Elleste Duet contains estradiol (oestrogen) for the first 16 days of each cycle, then estradiol combined with norethisterone (a progestogen) for the remaining 12 days. The progestogen phase protects the womb lining from thickening. You will have a withdrawal bleed at the end of each cycle, similar to a period.

Women in perimenopause or early menopause who are still having periods or have only recently stopped. Suitable for women who prefer a tablet over patches or gels. The 1mg strength is usually the starting dose; 2mg if symptoms are not adequately controlled. Not suitable for women more than 12 months post-menopause (consider continuous combined HRT instead).

Order online and we review your request. A prescriber checks your consultation form for clinical appropriateness and contacts you if anything else is needed. Once approved, your medication is dispensed and delivered to your door.

Tracked: Tracked delivery, arrives in two working days - Free

When it arrives: Every order is sent tracked. Where this page says in post today, it goes out today. Where it says in post tomorrow, it goes out the next working day. On the rare occasions a medicine is unavailable, we will contact you to talk about timing and alternatives.

We dispense clinically equivalent generic medications where available. Prices shown are for the generic version. If you prefer the branded version, let us know in your order form and we will confirm any price difference.

From £20.99 per month

Common: breast tenderness, headache, nausea, abdominal bloating, mood changes, withdrawal bleeding. Uncommon: weight changes, skin changes. Rare: VTE (small increased risk with oral oestrogen). Most side effects settle within 3 months of starting.

Known or suspected breast cancer, undiagnosed vaginal bleeding, active or recent VTE, untreated endometrial hyperplasia, active liver disease, porphyria.

CYP3A4 inducers (carbamazepine, phenytoin, rifampicin, St John's Wort) may reduce effectiveness. Thyroid replacement: may need dose adjustment.

Not for use in pregnancy or breastfeeding.

Take one tablet daily at the same time. Follow the colour-coded tablet order on the blister pack. Expect a withdrawal bleed towards the end of each pack. Do not stop abruptly. Regular breast screening and cervical screening should continue. Review your HRT with a prescriber at least annually.