In brief…
Oestrogel is an estradiol 0.06% gel applied daily to the skin. It is the single most prescribed HRT product in the UK, with over 1.3 million items dispensed in 2024/25. Body-identical oestrogen absorbed through the skin, avoiding first-pass liver metabolism. Usually combined with a progestogen such as Utrogestan if you have a womb.

Oestrogel
For Menopause & HRT
Strength
£24.99 (80g pump) per pack
Delivery
In post tomorrow. Tracked delivery, arrives in two working days.
What you need to know
Relief of menopausal symptoms including hot flushes, night sweats, vaginal dryness, mood changes, difficulty sleeping, and reduced libido. Also used for bone protection in women at risk of osteoporosis. Must be combined with a progestogen (e.g. Utrogestan) if you have a womb, to protect the womb lining.
Oestrogel delivers body-identical 17-beta estradiol through the skin (transdermal). This replaces the oestrogen your ovaries no longer produce after menopause. Transdermal oestrogen avoids first-pass liver metabolism, which means it does not increase clotting risk in the way oral oestrogen can. You apply 1-2 pumps daily to your inner arm or thigh.
Women experiencing menopausal symptoms, whether natural or surgical menopause. Particularly suitable for women with risk factors for blood clots, as transdermal oestrogen does not increase VTE risk. Also suitable for women with migraine, raised BMI, or liver conditions where oral oestrogen is less appropriate.
Order online and we review your request. A prescriber checks your consultation form for clinical appropriateness and contacts you if anything else is needed. Once approved, your medication is dispensed and delivered to your door.
Tracked: Tracked delivery, arrives in two working days - Free
When it arrives: Every order is sent tracked. Where this page says in post today, it goes out today. Where it says in post tomorrow, it goes out the next working day. On the rare occasions a medicine is unavailable, we will contact you to talk about timing and alternatives.
We dispense clinically equivalent generic medications where available. Prices shown are for the generic version. If you prefer the branded version, let us know in your order form and we will confirm any price difference.
From £24.99
Common: breast tenderness, headache, nausea (usually settles within 3 months). Uncommon: bloating, leg cramps, skin irritation at application site. Transdermal oestrogen does not carry the increased VTE risk associated with oral oestrogen. May cause irregular bleeding initially if starting HRT.
Known or suspected breast cancer, undiagnosed vaginal bleeding, active or recent VTE (unless on anticoagulants and using transdermal), untreated endometrial hyperplasia, active liver disease, porphyria.
CYP3A4 inducers (carbamazepine, phenytoin, rifampicin, St John's Wort) may reduce effectiveness. Thyroid replacement: may need dose adjustment. Transdermal route has fewer drug interactions than oral oestrogen.
Not for use in pregnancy or breastfeeding. Oestrogel is for menopausal women only.
Apply to clean, dry skin on your inner arm or thigh. Allow to dry before dressing. Do not apply to breasts. Avoid contact with others' skin for at least one hour after application. If you have a womb, you MUST take a progestogen alongside Oestrogel to protect your womb lining. Regular breast screening and cervical screening should continue as normal.
Safety information
Driving & machinery
Unlikely to affect driving.
Age restriction
Adults. HRT is most beneficial when started within 10 years of menopause or before age 60.
Storage
Store below 25°C in a dry place. Keep out of reach and sight of children. Do not use after the expiry date.
We're here to help
Not sure if this is right for you? Book a consultation. Online or in-person.
Report side effects
If you experience any side effects, report them via the MHRA Yellow Card Scheme or call 0800 731 6789.
Regulatory information
LoveMyLife Pharmacy is GPhC registered. View our regulatory information · Complaints procedure