Aciclovir

Genital herpes (first episode and recurrent), herpes simplex encephalitis, shingles (herpes zoster), chickenpox (in immunocompromised or severe cases), and cold sores (topical or oral).

Aciclovir is a nucleoside analogue that’s activated by the viral enzyme thymidine kinase (only present in infected cells). Once activated, it inhibits viral DNA polymerase, stopping viral replication. Because it’s only activated in infected cells, it has very low toxicity to normal cells.

Adults and children. Very safe drug. Dose adjustment needed in kidney impairment. Must be taken five times daily for herpes simplex, which is its main disadvantage (valaciclovir is the alternative with simpler dosing). Adequate hydration important.

Order online and we review your request. A prescriber checks your consultation form for clinical appropriateness and contacts you if anything else is needed. Once approved, your medication is dispensed and delivered to your door.

Tracked: Tracked delivery, arrives in two working days - Free

When it arrives: Every order is sent tracked. Where this page says in post today, it goes out today. Where it says in post tomorrow, it goes out the next working day. On the rare occasions a medicine is unavailable, we will contact you to talk about timing and alternatives.

We dispense clinically equivalent generic medications where available. Prices shown are for the generic version. If you prefer the branded version, let us know in your order form and we will confirm any price difference.

Aciclovir from £20.99 per pack.

Side effects vary. Common effects may include nausea, headache, and gastrointestinal disturbances. Please refer to the patient information leaflet supplied with your medication for a complete list. Report any unexpected or severe side effects to your prescriber or pharmacist.

Do not take this medicine if you are allergic to any of its ingredients. Inform your prescriber of all medical conditions, particularly liver or kidney disease, heart conditions, and any current medications. Always read the patient information leaflet.

This medicine may interact with other medications. Always inform your prescriber and pharmacist of all medicines you are taking, including over-the-counter medicines, supplements, and herbal remedies.

Consult your prescriber before taking this medicine if you are pregnant, planning pregnancy, or breastfeeding. Many medicines require careful assessment of risks and benefits during pregnancy.

Start as early as possible. Herpes simplex: 200mg five times daily for 5 days. Shingles: 800mg five times daily for 7 days. The five-times-daily dosing is inconvenient - set alarms. Drink plenty of water (to prevent crystallisation in kidneys). Very well-tolerated: nausea and headache occasionally. For suppression of recurrent genital herpes: 400mg twice daily long-term. Valaciclovir (Valaciclovir 500mg-1000mg) For Herpes & Shingles Aciclovir made simpler. Fewer tablets, same effect.