Fluconazole

Vaginal candidiasis (thrush), oral candidiasis, oesophageal candidiasis, fungal skin infections not responding to topical treatment, and systemic fungal infections.

Fluconazole inhibits fungal CYP450 enzyme lanosterol 14α-demethylase, blocking the production of ergosterol - an essential component of fungal cell membranes. Without ergosterol, the fungal cell membrane becomes leaky and the organism dies.

Adults and children. Single dose for vaginal thrush (OTC). Longer courses for other fungal infections. Important drug interactions (CYP2C9 and CYP3A4 inhibitor) - increases levels of warfarin, statins and many others. Caution in liver disease.

Order online and we review your request. A prescriber checks your consultation form for clinical appropriateness and contacts you if anything else is needed. Once approved, your medication is dispensed and delivered to your door.

Tracked: Tracked delivery, arrives tomorrow - Free

When it arrives: Every order is sent tracked. Where this page says in post today, it goes out today. Where it says in post tomorrow, it goes out the next working day. On the rare occasions a medicine is unavailable, we will contact you to talk about timing and alternatives.

We dispense clinically equivalent generic medications where available. Prices shown are for the generic version. If you prefer the branded version, let us know in your order form and we will confirm any price difference.

Fluconazole from £7.99 per pack.

Side effects vary. Common effects may include nausea, headache, and gastrointestinal disturbances. Please refer to the patient information leaflet supplied with your medication for a complete list. Report any unexpected or severe side effects to your prescriber or pharmacist.

Do not take this medicine if you are allergic to any of its ingredients. Inform your prescriber of all medical conditions, particularly liver or kidney disease, heart conditions, and any current medications. Always read the patient information leaflet.

This medicine may interact with other medications. Always inform your prescriber and pharmacist of all medicines you are taking, including over-the-counter medicines, supplements, and herbal remedies.

Consult your prescriber before taking this medicine if you are pregnant, planning pregnancy, or breastfeeding. Many medicines require careful assessment of risks and benefits during pregnancy.

Vaginal thrush: single 150mg capsule. Oral thrush: 50-100mg daily for 7-14 days. Can be taken with or without food. Check for drug interactions - especially with warfarin (can increase bleeding risk significantly), statins and some diabetes medications. Nausea, headache and abdominal pain can occur. Recurrent vaginal thrush (4+ episodes per year) may need a maintenance regimen.