Doxepin
For insomnia
The best-evidenced of its kind for staying asleep through the night.
In brief…
Doxepin is a sedating antidepressant. At low doses it is one of the best-evidenced medicines for helping people stay asleep through the night, and it is generally well tolerated.

Doxepin
For insomnia
Strength
£20.99 (28 capsules) per pack
Delivery
In post tomorrow. Tracked delivery, arrives in two working days.
What you need to know
Insomnia, particularly where the problem is waking in the night or too early rather than getting off to sleep in the first place.
Doxepin blocks histamine, the signal that keeps you awake. At the low doses used for sleep this gives a steady, well tolerated sedative effect that helps you stay asleep, with less of the next-day grogginess seen with some alternatives.
Adults whose sleep keeps breaking in the night. Not suitable in some eye, prostate and heart conditions; the prescriber checks this for you. Use the lowest effective dose in older adults.
Order online and we review your request. A prescriber checks your consultation for clinical appropriateness and may contact you if anything else is needed. Once approved, your medication is dispensed and delivered to your door.
Tracked: Tracked delivery, arrives in two working days - Free
When it arrives: Every order is sent tracked. Where this page says in post today, it goes out today. Where it says in post tomorrow, it goes out the next working day. On the rare occasions a medicine is unavailable, we will contact you to talk about timing and alternatives.
We dispense clinically equivalent generic medicines where available. If you prefer a branded version, tell us in your order form and we will confirm any price difference.
Doxepin from £20.99 per pack.
Common: morning drowsiness and dry mouth. Less common: blurred vision, constipation and dizziness. These anticholinergic effects matter more in older adults. Report anything unexpected to your prescriber or pharmacist.
Do not use with untreated narrow-angle glaucoma, significant urinary retention, or alongside a monoamine oxidase inhibitor. Tell your prescriber about heart, eye, prostate, liver and kidney conditions.
Adds to the effect of alcohol and other sedatives. Interacts with some antidepressants and medicines that affect heart rhythm. List everything you take, including over the counter and herbal products.
Tell your prescriber if you are pregnant, planning pregnancy or breastfeeding, so the risks and benefits can be weighed for you.
Take in the evening before bed. The dose for sleep is low, usually 25mg or less; a 25mg in 5ml liquid is available if a smaller dose suits you. Higher doses belong to the treatment of depression, not sleep, so follow the dose you are given. Avoid alcohol. Do not stop abruptly after long use without advice.
Safety information
Driving & machinery
May cause next-day drowsiness that can affect driving. Do not drive or operate machinery until you know how it affects you.
Age restriction
Adults 18 and over. Use the lowest effective dose in older adults.
Storage
Store below 25°C in a dry place. Keep out of reach and sight of children. Do not use after the expiry date.
We're here to help
Not sure if this is right for you? Book a consultation, online or in person.
Report side effects
If you experience any side effects, report them via the MHRA Yellow Card Scheme or call 0800 731 6789.
Regulatory information
LoveMyLife Pharmacy is GPhC registered. View our regulatory information · Complaints procedure