Promethazine Hydrochloride
For Allergy, Travel Sickness and Short-Term Sleeplessness
A sedating antihistamine for allergy and travel sickness.
In brief…
Promethazine (Phenergan) is an older, sedating antihistamine. It relieves allergy symptoms, prevents travel sickness and can help with short-term sleeplessness. It causes drowsiness that can last into the next day.

Promethazine Hydrochloride
For Allergy, Travel Sickness and Short-Term Sleeplessness
Strength
£14.99 (56 tablets) per pack
Delivery
In post today. Tracked delivery, arrives tomorrow.
What you need to know
Hay fever and allergic reactions such as hives, travel sickness, and occasional short-term difficulty sleeping.
Promethazine blocks histamine, which eases itch and allergy symptoms. It also acts on the brain's balance and sleep centres, which is why it helps with travel sickness and causes drowsiness.
Adults. Not suitable if you have severe liver disease or are taking an MAOI antidepressant. Use with care if you have epilepsy, glaucoma, prostate problems or breathing problems.
Order online and we review your request. A prescriber checks your consultation form for clinical appropriateness and contacts you if anything else is needed. Once approved, your medication is dispensed and delivered to your door.
Tracked: Tracked delivery, arrives tomorrow - Free
When it arrives: Every order is sent tracked. Where this page says in post today, it goes out today. Where it says in post tomorrow, it goes out the next working day. On the rare occasions a medicine is unavailable, we will contact you to talk about timing and alternatives.
We dispense clinically equivalent generic medications where available. Prices shown are for the generic version. If you prefer the branded version, let us know in your order form and we will confirm any price difference.
Promethazine Hydrochloride £14.99 per pack.
Side effects vary. Common effects may include nausea, headache, and gastrointestinal disturbances. Please refer to the patient information leaflet supplied with your medication for a complete list. Report any unexpected or severe side effects to your prescriber or pharmacist.
Do not take if you have taken an MAOI antidepressant in the last 14 days, have severe liver disease, or are in a coma. Take care with epilepsy, glaucoma, an enlarged prostate, or asthma and other breathing problems.
Increased drowsiness with alcohol, opioids, sleeping tablets, some antidepressants and other sedating medicines. Tell us every medicine you take.
Tell us if you are pregnant or breastfeeding. It is sometimes used in pregnancy for sickness on a doctor's advice, but it can make a breastfed baby drowsy.
Allergy: 25mg at night, or 10mg to 20mg two or three times a day. Travel sickness: 25mg the night before the journey. Sleeplessness: 25mg at bedtime for short-term use only. Do not drink alcohol. Do not drive or operate machinery if you feel drowsy, including the next morning. Not for long-term use for sleep.
Safety information
Driving & machinery
Check the patient information leaflet for advice on driving. Do not drive if you experience dizziness, drowsiness, or any other effects that may impair your ability.
Age restriction
Adults 18 and over unless otherwise directed by a prescriber.
Storage
Store below 25°C in a dry place. Keep out of reach and sight of children. Do not use after the expiry date.
We're here to help
Not sure if this is right for you? Book a consultation. Online or in-person.
Report side effects
If you experience any side effects, report them via the MHRA Yellow Card Scheme or call 0800 731 6789.
Regulatory information
LoveMyLife Pharmacy is GPhC registered. View our regulatory information · Complaints procedure