The Sinclair Method articles

Articles on how we work, written by our clinical team. Updated regularly.

Health | Care | Convenience

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Articles on naltrexone, the evidence, the practicalities, and what to expect.

For a full overview see our Sinclair Method service page.

Understanding the method

A woman in her 40s walking outdoors looking calm and hopeful, soft daylight What is the Sinclair Method? Sinclair Method vs Antabuse Sinclair Method vs Antabuse A young adult in their late 20s enjoying a social evening with a soft drink in hand, relaxed not isolated Does TSM work for binge drinkers?

Practicalities

South Asian couple at a small London cafe by a window. The Sinclair Method on the NHS South Asian couple at a small London cafe by a window. How much does naltrexone cost? A middle-aged woman sitting quietly at home with a mug looking out of a window TSM and AA together Mixed-heritage couple at a small London cafe by a window. How to get naltrexone prescribed in the UK

Taking the medication

A middle-aged man walking along a coastal path in soft evening light How long does TSM take? A South Asian woman sitting at a kitchen table reading treatment information Your first 14 days on TSM A South Asian man sitting quietly at home looking out of a window Naltrexone vs nalmefene

Safety and monitoring

A middle-aged man sitting at a train station looking at his phone Common side effects Mixed-heritage couple at a small London cafe by a window. Missing a dose Couple at a small London cafe in the morning. Liver function tests on TSM

Read across our other services

Adult out walking in London on a bright morning. Weight Management Confident older woman hiking by the coast, smiling and looking off into the distance. Menopause A man looking across hills and water at sunset during a hike Testosterone Contraception Contraception STI Testing - Articles STI testing Man in his late forties walking along a leafy residential London street on a sunny weekday morning. All articles A-Z

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